projects | Rahul Manoj, PhD

Algorithm Devlopment & Modelling

Digital Twins for Heart Faliure Diagnosis

Modelling pipeline integrating echocardiography, shear‑wave elastography, and hybrid physics/data‑driven models, delivering a validated decision‑support tool for early detection of heart‑failure pathology.

Credibility Assessment of Models

How to build a model we can trust? Established regulatory-aligned verification and validation (V&V) frameworks (as per ASME V&V 40) with a focus on Identifiability, Uncertainity Quanification and Sensitivity Analysis.

Calibartion-Free Blood Pressure Measurement

A calibration‑free, non‑invasive blood pressure (BP) estimation methods for large blood vessels by combining high frame rate ultrasound imaging (B-mode & A-mode) with Doppler flow velocity measurements and arterial tonometry.

Reflection-free Pulse Wave Velocity (PWV)

Improved measurement accuracy and precision of the pulse wave velocity (PWV) and its incremental variations within a cardiac cycle. Implimented wave reflections-compensated Pulse Trasit Time (PTT) for PWV computation.

Pulse Wave Decomposition (Carotid Artery)

Flow-independent modelling approaches (multi-Gaussian and multi-Rayleigh Flow Shape Models) for decomposing a measured pulse wave from carotid artery into its forward and backward components for quantifying pulse wave reflection.

Cepstral Analysis for Non-linear WSA

A novel Non-linear Pulse Wave Spearation Analysis (WSA) based on signal processing (homomorphic deconvolution) for quantifying the arterial pulse wave reflections from any measured pulse waveform, an alternative proposal to linear WSA.

Pulse Wave Analysis (Carotid/Aorta)

A set of algorithms for detailed feature detection of carotid and aortic pulse waveforms - idetifying fiducial points in upstroke, down stroke of pulse waveform from the derivative signals, dicrotic notch, Augmentation Index, pulse contour markers (a,b,c,d,e).

High Throughput Ultrasound Data Framework

A data structure framework designed to handle high frame rate ultrasound RF data from multi-channel acquisition systems, providing optimized binary file storage and reliable reconstruction for downstream signal processing. Codes and examples on how to read and write binary files.

Electronic Systems & Instrumentation

CW Doppler Flow Integration with ARTSENS

Integrated a continuous wave Doppler flow velocity measurement with the in-house developed ultrasound-based image-free cardiovascular screening tool (ARTSENS).

Multi-Modality Vascular Signals Instrumentation

Designed and validated multi-modal vascular probes & instrumentation combining custom-made single-element ultrasound transducers with strain-gauge sensors for measuring material properties of blood vessels.

Plane Wave Imaging with ARTSENS

Engineered a 4-channel custom made single element ultrasound probe in pulse echo mode for high frame rate plane wave imaging to capture the speed of travelling arterial pulse waves.

In-line Catheter Pressure & ECG Data Logger

A compact inline device that records high-fidelity pressure waveforms from fluid-filled catheters along with synchronized ECG signals without interfering with standard patient monitoring systems.

Hydrostatic Pressure Offset Correction Unit

A device for real-time hydrostatic pressure compensation that enables heart-level referenced blood pressure measurements across different anatomical sites.

Carotid Tonometry Measurement

Prototypes using resistive, capacitive and strain-gauge sensors for carotid and radial tonometry applications are developed. The effcet of hold-down pressure on the probe for signal quality is chacaterised.

Ambulatory Monitoring of Arterial Stiffness

On the go prototypes for self monitoring of day-to-day variations in vascular stiffness from the common carotid artery using photoplethysmography (PPG), acoustic photoplethysmography (aPPG) and accelerometers.

Ultrasound Transducer Characterization

Experiments to characterise the signal qualtiy, frequency spectrum, pulse width, resolution and attenuation of custum-made focused ultrasound trasducers.

Speed Control Drive for AC Motarised Load

Speed Control Drive System for AC motorized load, operates either in Temperature Feedback based Controller.

Electro-Mechanical Systems & Control

Bed-Integrated Body Weight Measurement

How to measure the weight of a bed-ridden patient? Designed and built a functional prototype of a modular and automatic time scheduled body weight measurement system for bedridden patients.

Excised Artery Mock Blood Circulation Rigs

Ex-vivo laboratory test rig platform using excised animal arteries for mock circulation loop of heart and systemic arteries

Silicone Tubings Mock Blood Circulation Rigs

In-vitro Laboratory test rig platform using Silicone tubes for mock circulation loop of heart and systemic arteries

Automated Cover-slipper for Tissue Slides

Developed software and integrated electronics, sensors and actuators for an in-house designed automated cover slipper for large-format (6'' X 8'') histopathology human brain section slides.

High Resolution Whole Slide Imaging

Prototype for high resolution Whole Slide Imaging (WSI) scanners for large format histopathology brain tissue slides.

Tele-operated Path Tracking Robots

Tele-operated control system of wheeled Mobile Robot, which tracks the path generated with the end effector of a 3DOF robot manipulator in real time uisng PID controls

ABU RoboCON Robots (Manual & Autonomous)

Design, Fabrication and Control of ABU ROBOCON India (National Level) Manual and Autonomous Robots for the year 2013, 2014 and 2015, as per the problem statement of the contest for each year.