1st Patent Granted on Cuffless and Calibartion-Free BP Meaqsurement System & Methods

In strict engineering terms, Blood Pressure (BP) is the wall stress experienced by the distensible blood vessel (arteries) walls due to pulsatile blood flow. High BP (Systolic BP) & and Low BP (Diastolic BP) are the maximum and minimum magnitude of the wall stress experienced by the vessel wall respectively in 1 heart cycle.
The complex heterogeneity of the circulatory system produces variations in BP, both in magnitude and shape of the continuous BP waveform throughout the body. Bottomline is BP varies throughout the body. Which BP should we measure?

Central BP (cBP) is the pressure experienced by vital organs, connected by the aorta and its direct branches. The cBP shown predictive potential in detecting the early manifestations of cardiovascular diseases and advance current hypertension management as opposed to the conventionally measured BP from the brachial artery (cuff around your upper arm). The problem is how to measure it non-invasively?

My first patent is a collection of instrumentation and bio-physics methods to measure the material property of the blood vessels and BP waveform in a cuffless and calibration-free approach non-invasively. I am happy to share that my first patent got granted. (Indian Patent No. 541544). Securing this patent is a testament to perseverance, innovation, and the incredible support from my colleagues and mentors - Dr. Jayaraj Joseph, Dr. Nabeel P. M., Dr. V. Raj Kiran and Prof. Mohanasankar Sivaprakasam at Healthcare Technology Innovation Centre, IIT Madras Research Park. The patent is a spin-off from my PhD work at the Indian Institute of Technology Madras.

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